Phosphatidylcholine (PC) is an essential lipid nutrient which is a primary constituent of all of our cell membranes. As such, phosphatidylcholine is important for virtually all body functions. If you can improve the health of cellular membranes, you improve the health of the organs, and the health of the person.

PC IV therapy is utilized to improve:

• Brain function
• Cardiovascular health
• Liver function
• Healthy aging
• Detoxification
• Autoimmune conditions
• Chronic Infection

CONDITIONS THAT MAY IMPROVE WITH PHOSPHATIDYLCHOLINE IV THERAPY:

• Cardiovascular disease: Phosphatidyl choline (PC) reduces inflammation which helps the cardiovascular system and it may also help to maintain healthy cholesterol levels.

Neurological conditions

• Cognitive problems/Dementia: The body makes a brain chemical called acetylcholine from phosphatidylcholine. Acetylcholine is important for memory.  Parkinson’s, Multiple Sclerosis Post-Stroke are also conditions which may benefit from PhosphatidylCholine.
• Liver disease-fatty liver: Research documented improvements with PC have been published https://pmc.ncbi.nlm.nih.gov/articles/PMC8960636/
• Chronic infections (Lyme disease): Due to immune-mediated and direct damage from Lyme disease, cell membranes throughout the body – including nerves – become damaged. Phosphatidylcholine repairs the damaged cell (and mitochondrial) membranes of nerves, restoring their ability to function properly.
• Chronic mold exposure: Phosphatidyl choline is a phospholipid that plays a crucial role in cell membrane integrity and detoxification. Infusing phosphatidyl choline supports liver function, enhances bile production, and aids in the elimination of toxins, including mold metabolites. By promoting liver detoxification pathways, PC helps to alleviate the burden of mold toxicity.
• Mast cell activation syndrome: phosphatidyl choline stabilizes cell membranes
• Advanced aging: Aging is one of the most complex biological processes. During aging, cellular membranes and the structure and cellular function of the body gradually decline, as susceptibility to disease and death increases [1].  The free radical theory of aging suggests that free radicals cause cellular damage and accumulation of this damage leads to aging in the organism [2]. There is a correlation between cellular ROS (reactive oxygen species) levels and an organism’s lifespan [3].   https://pmc.ncbi.nlm.nih.gov/articles/PMC6657616/  
• Autism and developmental delay: as a result of its benefit to nervous system cells, neurological difficulties may be improved.

Research has shown that Phosphatidylcholine may be helpful in repairing damage to the liver caused by alcohol, pollutants, and other toxins. And PC may have a protective effect on the mucosal lining of the gut with its anti-inflammatory effect. Phosphatidylcholine also enhances the body’s choline levels and increases brain acetylcholine formation.
Phosphatidylcholine is perhaps the most important essential molecule among tens of thousands of molecules that comprise a cell, accounting
for 50% of the cell membrane. PC IV treatment is for anyone who would like to improve cellular integrity and support a deep detoxification.
Phosphatidylcholine is generally well tolerated and most everyone can benefit from PC therapy. Replenishment with infused 

phosphatidyl choline improves cellular membrane function exports toxins out of the cells and helps to counter aging effects.

How Long Will It Take To See Improvement?

You may feel improvement right after the first IV session or more often the benefits be seen gradually over the first few weeks based on the individual’s conditions. Long term Health Benefits Since phosphatidylcholine is such an essential part of our cell membranes the benefits on a variety of the body’s systems should accrue to provide long standing health improvements.

Regular treatment helps with:

• Enhanced Cellular Function: Patients experience better cellular function and stronger intestinal lining integrity 
• Better Detoxification: Removes built-up toxins, including heavy metals and environmental pollutants 
• Improved Brain Health: Results show great progress in treating headaches, brain fog, and various neurological conditions 
• Liver Optimization: Patients demonstrate better liver function and natural detoxification processes
• Cardiovascular Health: Reducing inflammation and helping to maintain healthy cholesterol levels.

Neurological Conditions: Enhancing neuronal differentiation and ameliorates neuronal alterations caused by inflammatory conditions.

WHY GIVE PHOSHPHATIDYLCHOLINE AS AN IV?

After oral ingestion as a supplement phosphatidylcholine circulates to the liver, and while helpful for the liver, it cannot do for the rest of the body what an IV can do, delivering 100% of the biologically active phosphatidyl choline throughout the body.

HOW OFTEN AND FOR HOW LONG DOES ONE NEED TO HAVE PC IV TREATMENTS

This depends entirely on the level of need and difficulties of the patient regarding either the amount of toxic burden their body may be carrying, or in other cases the degree of dysfunction of their neurologic or systems being treated. To be effective, a minimum of 10 treatments is advised and often more. It is done once or twice per week, and the initial dose of 500mg will most often be increased as tolerated by the patient to 1,000mg or even 2,500mg. 

After the initial treatment period of 2 months, patients will often have maintenance doses spread out to between every 2 to 4 weeks.

For neurological conditions and detoxification, Glutathione IVs are often used as a companion therapy given as an ad-on during the same office visit.

PC Can Help Cognition 

A 2022 study tied phosphatidylcholine levels to Alzheimer’s disease.

It was published in the scientific journal BRAIN COMMUNICATIONS with the title: Serum unsaturated phosphatidylcholines predict longitudinal basal forebrain degeneration in Alzheimer’s disease. Another study published in 2016 study Trusted Source in mice with dementia, showed that different fatty acid compositions of phosphatidylcholine may help prevent a decline in memory and thinking ability. Human studies need to be done to better understand how phosphatidylcholine can help brain function.

It May Assist Healthy Liver Function – Research study was published with the following title, Regression of Liver Steatosis Following Phosphatidylcholine Administration https://pmc.ncbi.nlm.nih.gov/articles/PMC8960636/

A high fat diet may negatively affect your liver and may cause nonalcoholic fatty liver disease.
According to a 2022 research review Trusted Source, essential phospholipids rich in phosphatidylcholine are a common treatment for fatty liver disease. This scientific review also shows the clinical evidence that phosphatidylcholine can help to reverse this condition.

It Helps to Protect Against Medication Side Effects 

Long term use of some medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), can cause severe gastrointestinal side effects, including bleeding in the digestive tract.  A 2013 study Trusted Source publication showed that long-term NSAID use disrupts the phospholipid layer of the gastrointestinal tract, leading to gastrointestinal injury. Phosphatidylcholine may help prevent this NSAID-related gastrointestinal side effect.

It May Help Dissolve Gallstones 

Gallstones are usually made up of undissolved cholesterol or bilirubin. Without treatment, they may become lodged in your bile ducts and cause severe pain and may cause inflammation of your pancreas. In a 2003 study, phosphatidylcholine supplementation reduced cholesterol gallstone formation in mice that were fed a high cholesterol diet. https://www.rxlist.com/supplements/phosphatidylcholine.htm

Because the body uses phosphatidylcholine to make a brain chemical called acetylcholine, it has been investigated for treatment of conditions such as memory loss, Alzheimer’s disease, anxiety, manic-depressive disorders, and a movement disorder called tardive dyskinesia.

Phosphatidylcholine is also used for treating hepatitis, eczema, gallbladder disease, circulation problems, high cholesterol, and premenstrual syndrome (PMS); for improving the effectiveness of kidney dialysis; for boosting the immune system; and for preventing aging.

Phosphatidylcholine injections are now often compounded in pharmacies for injection therapies.

Ulcerative colitis (UC) causes inflammation in your digestive tract. It may also cause ulcers. According to a 2021 research analysis, delayed-release phosphatidylcholine could help improve quality of life in people with UC.

More information about neurologic function and PC

Phosphatidylcholine enhances neuronal differentiation and ameliorates neuronal alterations caused by inflammatory conditions. In experimental cellular growth media, phosphatidylcholine induces neurogenesis. and provides the morphological bases for synaptic plasticity to help the healing of neurological conditions often seen as conditions for which no effective treatment exists.The percentage of abnormal neurons decreases with Phosphatidylcholine treatment, resulting in a significantly increasing the presence of normal neurons. 

The Journal Scientific Reports reports: Phosphatidylcholine restores neuronal plasticity of neural stem cells under inflammatory stress. https://drsobo.com/phosphatidylcholine-promotes-neuronal-plasticity/

They review past studies as well as explain recent ones showing the importance of phospholipids, particularly phosphatidylcholine for the function and regeneration of neural cell membranes.

https://www.nature.com/articles/s41598-021-02361-5

Neural stem cells have a crucial role after nervous tissue damage, having the potential for regeneration owing to their capacity of self-renewal and differentiation into neurons. This ability is limited under pathological conditions due to the factors present in the wounded microenvironment that can affect Neuronal stem cells survival, proliferation and differentiation.

Scientific study provides evidence that Phosphatidylcholine treatment targets neuronal stem cells promoting the establishment of more functional neurons, restoring the morphological deficit caused by inflammation. Deeper study of the cellular mechanism leading to neuronal dysfunction under inflammatory conditions is essential for the development of novel therapies.