Side effects can occur with Tirzepatide as with all medications, but they are generally mild to moderate in severity. They include nausea, diarrhea or constipation. Vomiting may occur but is much less frequent. These are the only common side effects, while others occur rarely. As with many medications, side effects are related to the dosage that is used. As  a result patents are advised to start with a relatively low dose of 2.5 mg. Common practice is to increase the dose every weeks 4 weeks as tolerated. The higher dose is expected to be more effective for appetite control, and  thus patients generally increase their dose to 10mg  as long they are not limited by side effects. The maximum dose is 15mg .

Regarding the use of medication to achieve weight loss it has to be recognized that it is difficult for most people to make the necessary changes based on their determination and willpower. Therefore as stated by the spokesperson for Eli Lilly who produces the medication, “while intensive lifestyle intervention is an important part of ob esity management, these results underscore the difficulty some people face maintaining weight loss with diet and exercise alone.”

Monjauro’s success has been a game changer for so many people, and its popularity seems to keep increasing. One reason for it becoming so well known is that many prominent public figures in show business and industry have been open about the fact that they have used it for their own weight loss efforts.  It seems to have gotten to the point that when a prominent person loses weight they are suspected of having used this type of medication and are asked about it.

A similar medication originally developed for diabetes which doctors and their patients are using for weight control is called Ozempic, (GLP-1 agonist Semaglutide) . In addition to all of the ways in which people have become aware of both Mounjaro and Ozempic there is an even greater awareness of them related to the popularity of the variety of social media sites through which word of their effectiveness continues to spread.