Tesamorelin – A Peptide To Burn Belly Fat And Treat Fatty Liver

Peptide therapy has emerged as an effective treatment that can help patients with many different medical conditions. Tesamorelin is a growth hormone-releasing hormone (GHRH) peptide. Peptides are short-chain amino acids, many of which are produced naturally by the human body. Others have been synthesized as a growing body of evidence points to the therapeutic effectiveness of many different peptides. Amino acids are the building blocks of proteins. When the chain of amino acids is a chain of less than 50 amino acids they are categorized as peptides, whereas they are considered proteins when the chain exceeds 50 amino acids. These peptides engage in a multitude of physiologic processes and perform many tasks inside the body, thus producing benefits in a wide variety of conditions. By producing  some of the synthetically made versions of these amino acid chains, peptide therapy functions as important regenerative treatments that increase the effectiveness these substances provide to enhance the body’s ability to perform its own healing functions. Peptide therapy can be used to improve the immune system, act as a  natural anti-inflammatory, enhance cognitive functions, and assist in accomplishing weight loss and lowering body fat while preserving the body’s muscle mass.

Tesamorelin has been scientifically proven and recognized by the FDA  as a treatment to be used to reduce body fat. It was approved in 2010 to reduce abdominal fat accumulation seen in HIV patients diagnosed with lipodystrophy, a condition of fatty accumulation around the abdomen. https://search.app/zSHNajSvAbENqTeGA  Because of its fat burning actions Tesamorelin has been used as an excellent  weight loss treatment for non-HIV patients striving  to manage their weight and lower their body fat. Tesamorelin is also effective to treat  fatty liver disease 

How The Peptide Tesamorelin Works

Once Tesamorelin is administered, it stimulates the pituitary gland to release growth hormone. As we age many people will have their natural growth hormone production diminished, and this plays a part in certain phenomena seen with aging, such as loss of muscle tone and strength as well as an increase in body fat percentage. When growth hormone is released by the pituitary gland, it boosts metabolism and improves muscle mass, which helps to burn more calories, and it decreases a person’s body fat percentage. Tesamorelin has also been shown to reduce visceral adipose tissue, such as seen in a condition called  “fatty liver” and this leads to improvement in reducing overall body fat and waistline measurements.  Tesamorelin is being used to help manage obesity, and fatty liver disease.

Studies showing the effectiveness of Tesamorelin

In November 2010, the US FDA approved tesamorelin for the treatment of excessive abdominal fat in PLWH [20] [21]. In a double-blinded placebo controlled study tesamorelin decreased Visceral Abdominal Tissue (VAT) by 15% compared to placebo [2224]. It was also shown to reduce hepatic (liver )fat by 40% [25] for the patients with abdominal fat accumulation. https://pubmed.ncbi.nlm.nih.gov/21668043/

Another study documented that Tesamorelin therapy achieved significant improvement in body composition measurements as well as providing relief of body image difficulties reported by study subjects. Tesamorelin was well tolerated, with significant side effects occurring in less than 4% of patients over the 26 weeks of treatment. Most of these events were injection-site reactions or events known to be associated with growth hormone therapy such as  joint discomfort, headache and fluid retention. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766405/

Tesamorelin is typically provided to patients  in a powder form to be mixed with water and used as self administered injection. Once it has been reconstituted into a liquid, the mixture is stored in the refrigerator for the duration of the treatment. Tesamorelin injections are  given subcutaneously-which means just under the skin-under in the belly or in the thigh. Choosing the injection site, one should avoid an area that has scar tissue, bruising, or irritation.It is advised to rotate the injection site each time to avoid redness or irritation after the injection.

What Are the Benefits of Tesamorelin?

Because Tesamorelin can help stimulate human growth hormone production, patients can experience several benefits  such as:

  • Quicker recovery time after workouts
  • Increased muscle mass
  • Reduced visceral fat and treatment of fatty liver disease
  • Improved cognitive function
  • Reduced LDL cholesterol and improved cardiovascular system functioning-  tesamorelin has been shown to reduce the thickness of the inner layer of the carotid artery, in an attempt to reduce atherosclerotic vascular disease.

Who Should Use Tesmorelin ?

Anyone who wishes to improve their body physical composition, boost their immune system, and improve their overall health .

What Are the Side Effects?

Minor side effects may resolve themselves during treatment as your body adjusts to the medication. Possible Side Effects include: Swelling and fluid retention. Redness or bruising at the injection site.

Discontinue the medication if a rash or hives occur after injection.

Do Other Medications Interact With Tesamorelin?

Some medications that may interact with Tesamorelin and compromise the effectiveness of the medication. Make sure to discuss medications you are on with your physician.

  • Simvastatin
  • Prednisone
  • Cortisone
  • Cyclosporine

When Will A Person See Results From Using Tesamorelin?

This will vary depending on a number of factors, such as an individual’s physical condition, the dosage used, and the patient’s adherence to proper diet and exercise guidelines. The positive changes should become manifest within the first month of treatment. The studies showing benefits such as loss of visceral fat and effective treatment for fatty liver disease lasted 26 weeks.

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Medically reviewed by Dr. Henry C. Sobo, M.D

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