TESAMORELIN
Tesamorelin is a growth hormone-releasing hormone (GHRH) peptide. Peptides are short-chain amino acids, many of which are produced naturally by the human body. Others have been synthesized as a growing body of evidence points to the therapeutic effectiveness of many different peptides. Amino acids are the building blocks of proteins. When the chain of amino acids is a chain of less than 50 amino acids they are categorized as peptides, whereas they are classified as proteins when the chain exceeds 50 amino acids.
These peptides engage in a multitude of physiologic processes and perform many tasks inside the body, producing benefits in a wide variety of conditions. By producing some of the synthetically made versions of these amino acid chains, peptide therapy functions as important regenerative treatments that increase the effectiveness these substances provide to enhance the body’s ability to perform its own healing functions. Peptide therapy can be used to improve the immune system, act as a natural anti-inflammatory, enhance cognitive function, and assist in accomplishing weight loss and lowering body fat while preserving the body’s muscle mass.
Tesamorelin has been scientifically proven and recognized by the FDA as a treatment to be used to reduce body fat. It was approved in 2010 to reduce abdominal fat accumulation seen in HIV patients diagnosed with lipodystrophy, a condition of fatty accumulation around the abdomen. https://search.app/zSH
Because of its fat burning actions Tesamorelin has been used as an excellent weight loss treatment for non-HIV patients striving to manage their weight and lower their body fat. Tesamorelin is also effective to treat fatty liver disease
How The Peptide Tesamorelin Works
Once Tesamorelin is administered, it stimulates the pituitary gland to release growth hormone. As we age many people will have their natural growth hormone production diminished, and this plays a part in certain phenomena seen with aging, such as loss of muscle tone and strength as well as an increase in body fat percentage. When growth hormone is released by the pituitary gland, it boosts metabolism and improves muscle mass, which helps to burn more calories, and it decreases a person’s body fat percentage. Tesamorelin has also been shown to reduce visceral adipose tissue, such as seen in a condition called “fatty liver” and this leads to improvement in reducing overall body fat and waistline measurements. Tesamorelin is being used to help manage obesity, and fatty liver disease.
Studies Showing the Effectiveness of Tesamorelin
In November 2010, the US FDA approved Tesamorelin for the treatment of excessive abdominal fat in PLWH [20] [21]. In a double-blinded placebo controlled study Tesamorelin decreased Visceral Abdominal Tissue (VAT) by 15% compared to placebo [22–24]. It was also shown to reduce hepatic (liver )fat by 40% [25] for the patients with abdominal fat accumulation. https://pubmed.ncbi.nlm.nih.
Another study documented that Tesamorelin therapy achieved significant improvement in body composition measurements as well as providing relief of body image difficulties reported by study subjects. Tesamorelin was well tolerated, with significant side effects occurring in less than 4% of patients over the 26 weeks of treatment. Most of these events were injection-site reactions or events known to be associated with growth hormone therapy such as joint discomfort, headache and fluid retention. https://www.ncbi.
Tesamorelin is typically provided to patients in a powder form to be mixed with water and used as self administered injection. Once it has been reconstituted into a liquid, the mixture is stored in the refrigerator for the duration of the treatment. Tesamorelin injections are given subcutaneously-which means just under the skin-under in the belly or in the thigh. Choosing the injection site, one should avoid an area that has scar tissue, bruising, or irritation.It is advised to rotate the injection site each time to avoid redness or irritation after the injection.
What Are the Benefits of Tesamorelin?
Because Tesamorelin can help stimulate human growth hormone production, patients can experience several benefits such as:
- Quicker recovery time after workouts
- Increased muscle mass
- Reduced visceral fat and treatment of fatty liver disease
- Improved cognitive function
- Reduced LDL cholesterol and improved cardiovascular system functioning- Tesamorelin has been shown to reduce the thickness of the inner layer of the carotid artery, in an attempt to reduce atherosclerotic vascular disease.
Who Should Use Tesmorelin ?
Anyone who wishes to improve their body physical composition, boost their immune system, and improve their overall health
What Are the Side Effects?
Minor side effects may resolve themselves during treatment as your body adjusts to the medication. Possible Side Effects include: Swelling and fluid retention. Redness or bruising at the injection site. Discontinue the medication if a rash or hives occur after injection.
When Will A Person See Results From Using Tesamorelin?
This will vary depending on a number of factors, such as an individual’s physical condition, the dosage used, and the patient’s adherence to proper diet and exercise guidelines. The positive changes should become manifest within the first month of treatment. The studies showing benefits such as loss of visceral fat and effective treatment for fatty liver disease lasted 26 weeks.