All posts in Nutrition

Diet and Exercise May Reduce Beta Amyloid in the Brain, Lower Alzheimer’s Risk

Diet and Exercise May Reduce Beta Amyloid in the Brain, Lower Alzheimer’s Risk

A new study published in the  American Journal of Geriatric Psychiatry  indicates that a healthy diet and  regular physical activity  may reduce the buildup of a toxic protein Beta amyloid, which is associated with the development of Alzheimer’s Disease.

The research done by the UCLA’s Semel Institute for Neuroscience and Human Behavior studied 44 adults ranging in age from 40 to 85 who had mild memory changes but did not have the diagnosis of  dementia. The study used  PET scans to assess the amounts of plaque and tangles in the brain which are composed of Beta amyloid, whose buildup is an indicator of Alzheimer’s disease.

They found that several lifestyle factors were linked to lower levels of plaques and tangles on the brain scans. These factors are – maintaining a proper body weight, exercise,  and a Mediterranean diet. The Mediterranean diet is  rich in fruits, nuts, vegetables, legumes, and fish but low in meats and dairy, with mild to moderate alcohol consumption.

Dr. David Merrill, lead author of the study said, “The fact that we could detect this influence of lifestyle at a molecular level before the beginning of serious memory problems surprised us.”

Earlier studies have shown that a healthy lifestyle may result in delaying the onset of Alzheimer’s disease. But this new study is the first to show that these lifestyle factors directly influence the abnormal protein beta amyloid in people with subtle memory loss who do not have dementia. Dr Merrill says, “The study reinforces the importance of living a healthy life to prevent Alzheimer’s, even before the development of clinically significant dementia. This work lends key insight not only into the ability of patients to prevent Alzheimer’s disease, but also physicians’ ability to detect and image these changes.”

For more of the latest in nutritional/ lifestyle research check all of my blog posts at www.drsobo.com/blog

For the best care in Integrative Medicine call Henry C. Sobo, M.D., at 203-348-8805 or write us at optimalhalth@optonline.net

More

Brains of Overweight People ‘Ten Years Older’ Study Shows

Brains of Overweight People ‘Ten Years Older’ Study Shows

The team studied data from 473 individuals between the ages of 20 and 87, at the Cambridge Centre for Aging and Neuroscience.

Research study author Dr Lisa Ronan says, “As our brains age, they naturally shrink in size, but it isn’t clear why people who are overweight have a greater reduction in the amount of white matter. We can only speculate on whether obesity might in some way cause these changes… ”

Senior author Professor Paul Fletcher, says “We’re living in an aging population, with increasing levels of obesity, so it’s essential that we establish how these two factors might interact, since the consequences for health are potentially serious. It will also be important to find out whether these changes could be reversible with weight loss, which may well be the case.”

For more of the latest in nutritional/ lifestyle research check all of my blog posts at www.drsobo.com/blog

For the best care in Integrative Medicine call Henry C. Sobo, M.D., at 203-348-8805 or write us at optimalhalth@optonline.net

More

Nut Consumption Reduces Inflammation

Nut Consumption Reduces Inflammation

A new study published in American Journal of Clinical Nutrition showed that dietary intake of nuts is associated with lower levels of the biomarkers of inflammation. This study of than 5,000 people by the  Brigham and Women’s Hospital  may help to explain the documented health benefits of nuts.

Research study author Ying Bao M.D. ScD, says, “Population studies have consistently supported a protective role of nuts against cardiometabolic disorders such as cardiovascular disease and type 2 diabetes, and we know that inflammation is a key process in the development of these diseases. Our new work suggests that nuts may exert their beneficial effects in part by reducing systemic inflammation.”

For this study, the research team performed  an analysis of data using dietary questionnaires, comparing the levels of the  proteins known as biomarkers in blood samples collected from the study subjects. The biomarkers of inflammation that were affected were, C-reactive protein (CRP) and interleukin 6 (IL6) .

The data revealed that those who had consumed at least five  servings of nuts per week had lower levels of CRP and IL6 than those who rarely or almost never ate nuts. Dr Bao says, “Much remains unknown about how our diet influences inflammation and, in turn, our risk of disease. But our study supports an overall healthful role for nuts in the diet and suggests reducing inflammation as a potential mechanism that may help explain the benefits of nuts on cardiometabolic diseases.”

For more of the latest in nutritional/ lifestyle research check all of my blog posts at www.drsobo.com/blog

For the best care in Integrative Medicine call Henry C. Sobo, M.D., at 203-348-8805 or write us at optimalhalth@optonline.net



More

Vitamin D Benefits People with Multiple Sclerosis

Vitamin D Benefits People with Multiple Sclerosis

It has long been known that  vitamin D deficiency is linked to an increased risk of developing Multiple Sclerosis. And also, it has been shown that people who already have MS and low levels of vitamin D are more likely to have greater disability and a worse prognosis in terms of the progression of the disease.

Another study showing the relationship of Vitanin D and  Multiple Sclerosis has been published in the Journal Neurology.

Researchers at Johns Hopkins gave the study subjects, 40 people with relapsing-remitting MS, either 10,400 IU  or 800 IU of vitamin D3 supplements daily for six months.  Blood tests at the start of the study and again at three and six months measured the amount of vitamin D in the blood and the response in the immune system’s T cells, which play a key role in MS. The people taking the high dose had a reduction in the percentage of inflammatory T cells related to MS severity,  The people taking the low dose did not have any noticeable changes in the percentages of their T cell subsets.

“We hope that these changes in inflammatory T cell responses translate to a reduced severity of disease,” said lead study author Peter Calabresi, MD.  “Other clinical trials are underway to determine if that is the case. More research is needed to confirm these findings with larger groups of people and to help us understand the mechanisms for these effects, but the results are promising. Vitamin D has the potential to be an inexpensive, safe and convenient treatment for people with MS”.

For more of the latest in nutritional/ lifestyle research check all of my blog posts at www.drsobo.com/blog

For the best care in Integrative Medicine call Henry C. Sobo, M.D., at 203-348-8805 or write us at optimalhalth@optonline.net

 

 

 

Johns Hopkins Medicine.

  1.  P. A. Calabresi. Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis. Neurology, 2015; DOI
More

Drinking Coffee Not Likely Harmful, May Be Beneficial Study Suggests

Drinking Coffee Not Likely Harmful, May Be Beneficial Study Suggests

Newly published research from the scientific journal Comprehensive Reviews in Food Science and Food Safety  concludes that moderate coffee drinking has a neutral effect on health, or it is may be mildly beneficial.

Drinking coffee is a staple in our society. Research over the years has been inconsistent with some studies showing beneficial effects and others creating concerns for coffee drinkers.

This study by researchers at Ulster University was published with the title A Comprehensive Overview of the Risks and Benefits of Coffee Consumption. It reviewed 1,277 studies published over the past 45 years on the effects of coffee consumption on human health.

The review was done hoping do define what potential health benefits or risks of coffee consumption might have on the variety of health outcomes that have been studied over the years;

– Total Mortality – Cardiovascular Disease – Cancer – Metabolic Health – Neurological Disorders- Gastrointestinal Conditions – Others

Their conclusion taking into account the great number of studies published over the years, was that the scientific consensus revealed by the data is that moderate coffee drinking, defined as 3-4 cups per day, has a neutral or a mildly beneficial effect on the drinker’s health.

Further research would be needed to further quantify the effect of coffee consumption on specific health outcomes .

 

For more of the latest in nutritional/ lifestyle research check all of my blog posts at www.drsobo.com/blog

For the best care in Integrative Medicine call Henry C. Sobo, M.D., at 203-348-8805 or write us at optimalhalth@optonline.net

More

Obesity linked to increased risk of multiple sclerosis

Obesity linked to increased risk of multiple sclerosis

Research published in PLOS Medicine by Dr. Brent Richards of the Jewish General Hospital, Quebec, shows that obesity in early adulthood is associated with an elevated  risk of developing multiple sclerosis (MS).  MS is a progressive neurological disorder which involves immune system dysfunction resulting in damage to the myelin sheath which surrounds the nerves in the spinal cord and the brain.

The team, composed of researchers in Canada and the UK, investigated whether genetically determined obesity was associated with a greater risk of developing Multiple Sclerosis.

“These findings may carry important public health implications because of the high prevalence of obesity in many countries”

Taking into account that other previous research pointing in this direction Drs. Alberto Ascherio and Kassandra L. Munger say that this helps to confirm that indeed, obesity in early life is causally related to the risk of developing multiple sclerosis risk and provides a further rationale for obesity prevention.”

What their research found was that an increase in  body mass index from the overweight to the obese category   an average size adult woman increasing in weight from approximately 150 to 180 pounds) was associated with an increase of about 40% in the risk of MS.

More

Drinking More Water Associated With Weight Loss and Health Benefits

Drinking More Water Associated With Weight Loss and Health Benefits

A new study  published in the Journal of Human Nutrition and Dietetics  from the University of Illinois found that people who increased their water consumption by one to three cups per day decreased their calorie intake up to 205 calories per day.They also consumed up to 18 grams less sugar per day as well as decreasing both their cholesterol and sodium intake .

Study author, community health professor Ruopeng An states , “the impact of plain water intake on diet was similar across race/ethnicity, education and income levels and body weight status. This finding indicates that it might be sufficient to design and deliver universal nutrition interventions and education campaigns that promote plain water consumption in replacement of beverages with calories in diverse population subgroups without profound concerns about message and strategy customization.”

Study participants were asked to recall everything they ate or drank over the course of two days.

Professor An calculated the amount of plain water each person consumed .On average, participants consumed about 4.2 cups of plain water on a daily basis . Those who consumed more than that were shown to eat less calories per day as well as lower their sugar, cholesterol and sodium intake.

Many have heard the long touted advice to drink 8 glasses of water per day to lose weight and for better health. This research ads scientific credibility to that old time suggestion.

For more of the latest in nutritional/ lifestyle research check all of my blog posts at www.drsobo.com/blog

For the best care in Integrative Medicine call Henry C. Sobo, M.D., at 203-348-8805 or write us at optimalhalth@optonline.net

More