The following is adapted from lectures given by Dr. Sobo at the Wainwright House in Rye, N.Y. and the Total Life Care Center in Norwalk, CT.
Theories of Aging
There are two basic types:
- Genetically programmed aging: Telemorase Theory
- Progressive damage aging: Free Radical Theory and Neuroendocrine Theory
The future is here ! Treating a variety of conditions with stem cells is a subject of intense investigation with hundreds of research studies being conducting all around the world. The hope is that stem cell therapy can help autoimmune diseases, neurologic disorders, diabetes, heart disease, the ravages of aging, and many other medical conditions.
A new study from the Departments of Biology and Physics at York, which was funded by Arthritis Research UK , has been published in the the journal Stem Cell Reports. They report having identified individual stem cells that can regenerate tissue, cartilage and bone. This knowledge opens the way to having better treatment for arthritis. Many clinical practitioners utilizing these therapies in advance of their general approval by the medical community report that they have helped many people avoid joint replacement surgery.
Lead researcher Dr Paul Genever says, “While stem cell therapy is an exciting new development for the treatment for osteoarthritis, up to now it has been something of a lottery because we did not know the precise properties of each of the cells. This project has helped us to establish which cells are good at regenerating tissue, cartilage and bone respectively. It will help in the search to develop more targeted therapies for arthritis patients.”
Dr James Fox one of the co-authors says, “Working with colleagues across the Arthritis Research UK Tissue Engineering Centre will help to bring our discovery closer to patient treatment.”
Director of Research at Arthritis Research UK Dr Stephen Simpson tells us that “There are 8 million people in the UK living with the pain and disability caused by osteoarthritis. We are fighting to find better treatments and one day, a cure. This research is exciting and promising. Identifying specific stem cells that could help the damaged joint to repair itself, takes us a step closer to our aim of developing an injectable, safe, stem cell therapy for people with osteoarthritis.”
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A new study published in the Journal of the American Medical Association Neurology finds a strong association between insulin resistance and decline in memory function, and the development of Alzheimer’s disease. The fact that obesity increases the risk of heart disease and some cancers is well known, but this study alerts us that the risk of memory loss is also a consequence we need to understand and act upon. Insulin resistance is common in people who are obese or pre-diabetic .
An article by a panel of experts has been published in the British Journal of Nutrition, explaining how nutrition influences inflammatory processes, and that controlling inflammation will help reduce the risk of many chronic diseases.
Researchers at the Fred Hutchinson Cancer Research Center have found that weight loss, in combination with vitamin D supplements, has a greater effect on reducing chronic inflammation than weight loss alone. Chronic inflammation is known to contribute to the development and progression of many diseases including cancer, and being overweight has been associated with a state of chronic inflammation.
Research published in the American Journal of Clinical Nutrition, shows that higher vitamin C concentrations in the blood, which result from eating fruits and vegetables, is associated with a reduced risk of heart disease and early death.
Fish oil and antioxidant supplementation might be beneficial for people in the early stages of dementia. A study just published in the July 2015 issue of the scientific journal of the American Federation of American Societies for Experimental Biology showed that people with mild dementia showed signs of improvement given these substances.
Reacting positively to stressful situations may play a key role in maintaining good health. A new study published in the journal Health Psychology finds that those who fail to maintain positive attitudes when faced with the minor stressful events of daily living have elevated levels of inflammation.
A new study done at the University of California at Berkeley provides more evidence that as previously suspected, poor sleep is associated with the development of Alzheimer’s Disease. Deposits of a toxic protein called beta-amyloid has long been thought to be causative of the death of brain cells leading to Alzheimer’s disease. When a person lacks deep restorative sleep the build up of this toxic protein is promoted.
A study just published in the Journal of The American Medical Association showed that giving folic acid to patients taking medication for high blood pressure significantly reduced the risk of having a stroke.